Current Topics
RoundTable at the End of the Trump Regime!
by Irked
1 second ago
Mars
by Irked
11 minutes 43 seconds ago
Another reason for impeachment
by pondering_it_all
49 minutes 11 seconds ago
investigation into the storming of the United States Capitol on 1/6/21
by jgw
Yesterday at 07:17 PM
3 word story game
by TatumAH
Yesterday at 04:57 PM
Why some kids stick with their parents' political views and others rebel
by pondering_it_all
Yesterday at 10:23 AM
Wizard of Oz
by TatumAH
02/23/21 03:49 AM
Global warming predictions
by jgw
02/22/21 07:43 PM
Slavery in 2020
by jgw
02/22/21 07:33 PM
Doctors fighting back against anti-vaxers online
by pondering_it_all
02/22/21 03:35 AM
Myanmar/Burma
by jgw
02/21/21 07:11 PM
It’s Not You, It’s Pathological Ambivalence!
by logtroll
02/21/21 03:51 AM
‘Earthworm Dilemma’ Has Climate Scientists Racing to Keep Up
by TatumAH
02/20/21 05:31 PM
And Then the Gorillas Started Coughing
by pondering_it_all
02/19/21 10:06 PM
Politics- sailing on the Sea of Insanity
by TatumAH
02/19/21 03:24 PM
An amusement - no politics!
by TatumAH
02/19/21 02:33 AM
American Healthcare
by pondering_it_all
02/16/21 03:41 AM
The Trump Era's silver lining
by pdx rick
02/15/21 04:41 PM
Did Trump think his mob had taken Mike Pence hostage?
by rporter314
02/15/21 04:58 AM
Are the Republicans confabulated?
by TatumAH
02/11/21 12:03 AM
Forum Stats
6292 Members
61 Forums
17081 Topics
306650 Posts

Max Online: 294 @ 12/06/17 12:57 AM
Google Adsense
Page 3 of 3 < 1 2 3
Topic Options
Rate This Topic
#332573 - 02/20/21 03:25 AM Re: Doctors fighting back against anti-vaxers online [Re: TatumAH]
pondering_it_all Offline
veteran

Registered: 02/27/06
Posts: 10874
Loc: North San Diego County
So that's why dialysis patients die. Much more complicated than I thought.

I have a weird condition where I often have sugar in my urine, but I never have a positive A1C. If I eat a lot of sugar, my kidney's seem to piss it out very efficiently. This has always been the case, from childhood. I have a familial history of diabetes. I also have peripheral afferent neuropathy (numb feet) from myelin degeneration.

My neurologist says neuropathy is not a symptom of my MS. Is it possible to have diabetic neuropathy without a positive A1C? Or do I just have an autoimmune reaction to myelin?

To top that off, my wife has an undiagnosed (or rather multiple different diagnoses) autoimmune condition against maybe connective tissue? Maybe against something else?

There is a possibility that both of our problems are the same unknown pathogen since she was a Veterinary Pathologist and could have been exposed to something weird that I caught. Her problem could be an unknown parasite since artemisia seems to help her cyclic episodes.

Top
#332575 - 02/20/21 03:54 AM Re: Doctors fighting back against anti-vaxers online [Re: pondering_it_all]
TatumAH Online   content
journeyman

Registered: 02/18/11
Posts: 768
Loc: Upstate NY
Idiopathic Glycosuia

Idiopathic peripheral neuropathy, is common and is diagnosed by ruling out toxin exposure, lead, paint, etc and DM. The nerves to the feet are the longest in the body, and is a long supply line vulnerable to many many insults. So not DM neuropathy. CNS and PNS myelin are different, so doubt autoimmune neuropathy related to MS.

Some autoimmune conditions are related to molecular mimicry when some bacteria or virus resembles a human tissue antigen and mistakenly gets attacked!



Edited by TatumAH (02/20/21 05:25 AM)
_________________________
There's nothing wrong with thinking
Except that it's lonesome work
sevil regit

Top
#332620 - 02/20/21 08:23 PM Re: Doctors fighting back against anti-vaxers online [Re: TatumAH]
pondering_it_all Offline
veteran

Registered: 02/27/06
Posts: 10874
Loc: North San Diego County
Obviously I have a lot of relatively harmless defects. Renal glycosuria sounds like a winner. I am a little concerned about this:

Quote:
In most affected individuals, no treatment is required. However, some individuals with renal glycosuria may develop diabetes mellitus. (For further information, please see the "Related Disorders" section above.. Therefore, appropriate testing should be conducted to rule out diabetes and to regularly monitor those with confirmed renal glycosuria.


The problem is that doctors always look at A1C to tell if you have DM, but the renal glycosuria prevents a positive A1C! The two conditions could be unrelated, but having one prevents diagnosis of the other.

Top
#332621 - 02/20/21 08:47 PM Re: Doctors fighting back against anti-vaxers online [Re: pondering_it_all]
TatumAH Online   content
journeyman

Registered: 02/18/11
Posts: 768
Loc: Upstate NY
The defect would likely prevent the complications of DM, as it's the long term elevation of serum glucose that causes all the problems to, vascular, renal, and nerves! In fact one of the newer treatments, i furget the trade name, is a medication that blocks the renal
re-absorption of glucose. and dumps glucose into the urine, improving the serum glucose levels.
_________________________
There's nothing wrong with thinking
Except that it's lonesome work
sevil regit

Top
#332622 - 02/20/21 09:06 PM Re: Doctors fighting back against anti-vaxers online [Re: TatumAH]
TatumAH Online   content
journeyman

Registered: 02/18/11
Posts: 768
Loc: Upstate NY
Google to the rescue!

Canagliflozin, Dapagliflozin, and Empagliflozin, OH MY! That's why I couldn't remember their names, I would never waste brain RAM on a bunch of, pardon the term, Copycat drugs!

Quote:

Sodium-glucose Cotransporter-2 (SGLT2) Inhibitors

SGLT2 inhibitors are a class of prescription medicines that are FDA-approved for use with diet and exercise to lower blood sugar in adults with type 2 diabetes. Medicines in the SGLT2 inhibitor class include canagliflozin, dapagliflozin, and empagliflozin. They are available as single-ingredient products and also in combination with other diabetes medicines such as metformin. SGLT2 inhibitors lower blood sugar by causing the kidneys to remove sugar from the body through the urine. The safety and efficacy of SGLT2 inhibitors have not been established in patients with type 1 diabetes, and FDA has not approved them for use in these patients.



Edited by TatumAH (02/20/21 09:10 PM)
_________________________
There's nothing wrong with thinking
Except that it's lonesome work
sevil regit

Top
#332688 - 02/22/21 03:35 AM Re: Doctors fighting back against anti-vaxers online [Re: TatumAH]
pondering_it_all Offline
veteran

Registered: 02/27/06
Posts: 10874
Loc: North San Diego County
Cool! So I already have that capability without the expensive prescription.

Quote:
it's the long term elevation of serum glucose that causes all the problems to, vascular, renal, and nerves


I was hoping that was the case, but sometimes what we hope for is not the total situation.

On another good news topic, I like to watch TWIV (This Week In Virology) on YouTube. Once a week they hear from Dr. Griffin who is a honcho of docs treating Covid-19 patients every day. This week he mentioned the benefits of treating admitted patients with 25(OH)-Vitamin D, as discussed by the Spanish trials. He also mentioned this later when he was discussing GPs treating Covid19 outpatients instead of just sending them home to isolate until they either get better or worse and need hospitalization.

He also said people who get vaccinations and soon after discover they have been exposed right around that time, tend to do better than those who don't get vaccinations. So immunity may not begin much before 14 days post vaccination, but apparently just giving your immune system a few days jump on it's response is useful.

Some do that now with people bitten by rabid animals on the extremities, since the immune system can be faster than the rabies virus getting into the central nervous system. Facial bites are more urgent. They require quick treatment with antibodies.

Top
Page 3 of 3 < 1 2 3

Who's Online
1 registered (TatumAH), 68 Guests and 7 Spiders online.
Key: Admin, Global Mod, Mod
Newest Members
Superfly, GreatNewsTonight, danarhea, RoughDraft274, CPWILL
6292 Registered Users
A2