There are many medications being proposed as potentially repurposed (existing drugs for other conditions that might work for COVID-19.

This thread is started as a place to talk about new research, results from existing randomized controlled trials, promising news about medications, etc.

Studies already published have included repurposed drugs, as listed below.

These are mainly against non-structural proteins of SARS-CoV2: the main 3C-like protease (Lopinavir, Ritonavir, Indinavir, Atazanavir, Nelfinavir, and Clocortolone), RNA-dependent RNA polymerase (Remdesivir and Ribavirin), and the papain-like protease (Mycophenolic acid, Telaprevir, Boceprevir, Grazoprevir, Darunavir, Chloroquine, Hydroxychloroquine, and Formoterol).

The best-documented multi-target drugs repurposed for COVID-19 therapy are as follows: antiviral drugs commonly used to treat AIDS/HIV (Atazanavir, Efavirenz, and Dolutegravir Ritonavir, Raltegravir, and Darunavir, Lopinavir, Saquinavir, Nelfinavir, and Indinavir), HCV (Grazoprevir, Lomibuvir, Asunaprevir, Ribavirin, and Simeprevir), HBV (Entecavir), HSV (Penciclovir), CMV (Ganciclovir), parasites (Ivermectin), bacterial infections (Azithromycin) and Ebola (Remdesivir), anticoagulant drug (Dabigatran), and an antifungal drug (Itraconazole).


Edited by GreatNewsTonight (05/03/20 05:13 AM)
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Please take COVID-19 seriously; don't panic but don't deny it; practice social distancing (stay 6ft from people); wash your hands a lot, don't touch your face, don't gather with too many people, so that you help us contain it.